Set registrants will have access to the eLearning archived modules (1–6). As part of your registration you will have unlimited access to each individual webinar recording for 30 days. The 30-day access will begin when you access each individual archive link. Certificates will be provided for each module. If you have any additional questions about the webinar set registration, please contact ACT Headquarters.
See Modules 1–6 
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Basic Toxicology Principles: Part 1
Speaker: A. Wallace Hayes, PhD, DABT, FATS, FRSB, FACFE, ERT
Registration for Archive is Closed
Topics include: Dose response, routes, test systems, and basics of study design
About the Expert Speaker: A. Wallace Hayes, PhD, DABT, FATS, FRSB, FACFE, ERT
Dr. Hayes is a toxicologist with over 35 years of experience in industry and academics. He holds degrees from Auburn University (PhD and MS) and Emory University (AB). Dr. Hayes was a NSF predoctoral fellow at Auburn University, a NIH individual postdoctoral fellow at the Vanderbilt University School of Medicine, a NATO Senior Scientist at the Central Veterinary Laboratory in Weybridge, England and held a NIH Research Career Development Award.
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Basic Toxicology Principles: Part 2
Speaker: A. Wallace Hayes, PhD, DABT, FATS, FRSB, FACFE, ERT
Registration for Archive is Closed
Topics include: Expression of toxicity, target organ toxicity, and normality; how to define and maintain it
About the Expert Speaker: A. Wallace Hayes, PhD, DABT, FATS, FRSB, FACFE, ERT
Dr. Hayes is a toxicologist with over 35 years of experience in industry and academics. He holds degrees from Auburn University (PhD and MS) and Emory University (AB). Dr. Hayes was a NSF predoctoral fellow at Auburn University, a NIH individual postdoctoral fellow at the Vanderbilt University School of Medicine, a NATO Senior Scientist at the Central Veterinary Laboratory in Weybridge, England and held a NIH Research Career Development Award.
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Pharmacology and Safety Pharmacology
Speaker: Jean-Pierre Valentin, PhD, HDR, ERT, CBiol, FRCPath, DSP
Registration for Archive is Closed
Topics include: Receptors, targets and off target, constants, consequences (including toxicity), testing, low-level effects, and aspects of interpretation (View Abstract  )
About the Expert Speaker: Jean-Pierre Valentin, PhD, HDR, ERT, CBiol, FRCPath, DSP
Jean-Pierre holds a PhD in Physiology and Pharmacology 1990, from the University of Montpellier, France. Following a postdoc at UCSF, Jean-Pierre joined the Pierre Fabre Research Centre (1992–98) where he contributed to the discovery and progression into development of three candidate drugs. He joined AstraZeneca to build from inception, develop and lead the Department of Safety Pharmacology where he contributed to the safety evaluation of ~200 candidate drugs across a wide range of therapy areas, leading to the development and successful registration of several marketed products. In February 2014 he joined UCB-Biopharma as Senior Director Head of Investigative Toxicology, based in Belgium. He is a member of several scientific societies; current Past President of the Safety Pharmacology Society; co-chair of the HESI subcommittee on QT/Arrhythmia, and the ABPI-NC3Rs-Animal Model Framework. He is involved in training and education programs and is author/co-author of several patents and >180 peer review publications and book chapters.
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Pharmacokinetics/ADME
Speaker: Gerry Kenna, PhD, FBTS
Registration for Archive is Closed
Topics include: Basic principles of absorption, disposition, excretion, biotransformation, membrane transporters, pharmacokinetics and toxicokinetics, and species differences and their role in hazard and risk assessment
About the Expert Speaker: Gerry Kenna, PhD, FBTS
Dr. Gerry Kenna is a Drug Safety Consultant based in Cheshire, United Kingdom. He has extensive experience of safety assessment of pharmaceuticals and other chemicals and of toxicity testing and of mechanisms that underlie human adverse drug reactions, most notably liver toxicity. This was acquired while working as Scientific Director of the Fund for the Replacement of Animals in Medical Experiments; in industry for AstraZeneca, Syngenta and Zeneca; and in academia at Imperial College School of Medicine, London UK; National Institutes of Health, MD USA; King’s College Hospital Medical School, London UK and the National Institute for Medical Research, London UK. Dr. Kenna continues to be actively involved in research on the mechanisms which underlie human adverse drug reactions and on the development and implementation of novel predictive safety screening strategies that take account of metabolic bioactivation, hepatobiliary transporter inhibition and immune responsiveness, plus PBPK-based in vitro/in vivo exposure scaling. He is also committed to implementation of improved human safety testing strategies that reduce, refine and replace a need for procedures on animals. Dr. Kenna received a BSc in Biochemistry from the University of Leeds UK and a PhD in Biochemistry from the University of London UK. He has authored or co-authored >100 scientific publications and is a member of the International Society for the Study of Xenobiotics, and a Fellow of the British Toxicology Society.
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General Toxicity
Speaker: Ruth Roberts, PhD, ATS, FBTS, ERT, FSB, FRCPath
Registration for Archive is Closed
Topics include: Test systems, test design, investigations—in life, in lab, termination, and aspects of interpretation (View Abstract )
About the Expert Speaker: Ruth Roberts, PhD, ATS, FBTS, ERT, FSB, FRCPath
Professor Roberts is a toxicologist with world-leading expertise in toxicology, drug discovery, drug development and molecular toxicology. She gained a BSc and PhD from Manchester University followed by postdoctoral research at the Imperial Cancer Research Fund. She joined ICI Central Toxicologist in 1990 as a cancer biologist and toxicologist where she led work into the molecular mechanisms of nongenotoxic carcinogenesis, leading to her being awarded the SOT Achievement award in 2002 followed by the EUROTOX Bo Holmsted award in 2008. Ruth was Director of Toxicology for Aventis in Paris (2002–2004) then joined AstraZeneca in 2004 where she was Global Head of Regulatory Safety, overseeing nonclinical safety input into >200 drug projects at all stages of discovery and development. Ruth left AstraZeneca in 2014 to set up ApconiX, an integrated toxicology and ion channel business delivering innovative approaches to drug safety evaluation. With >130 publications, Ruth is Council member of SOT, past president of the British Toxicology Society and past president of EUROTOX.
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Genotoxicity
Speaker: George Johnson, PhD
Registration for Archive is Closed
About the Expert Speaker: George Johnson, PhD
Dr. George is a steering member of the International Life Science Institute (ILSI) Health and Environmental Sciences Institute (HESI) Genetic Toxicology Technical Committee (GTTC) and co-chair of the quantitative subgroup. Dr. Johnson has been lead academic on numerous international collaborations. These include FDA-NCTR, Health Canada, RIVM-Netherlands, AstraZeneca, Drugs for Neglected Disease Initiative (DNDi), Food Standards Agency, GlaxoSmithKline, Gentronix, Hoffman-La-Roche, Litron, PBR-Labs Inc., and more. He also continues to co-lead the DNA damage group (In Vitro Toxicology Group) in the Institute of Life Science, as well as teaching on the genetics and medical genetics BSc degree schemes, and having a role as Director of Employability and Entrepreneurship for the College of Medicine.
George was awarded the prestigious UKEMS Young Scientist Award in 2012, in 2013 he became a Fellow of the Higher Education Academy, and in 2014 he became a British & European Registered Toxicologist and also won the prestigious EEMS Young Scientist Award.
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