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2019 Educational Course

Practical Reproductive and Developmental Toxicology

Hosted by the American College of Toxicology and Teratology Society

Course Description

This joint American College of Toxicology/Teratology Society course is designed to provide a basic understanding in reproductive and developmental biology and principles of various testing approaches for reproductive and developmental toxicology, with strong emphasis on the practical application of these principles and interpretation of nonclinical safety data as well as risk assessment. The intended audience for this course includes industrial and regulatory scientists, graduate students, and postdoctoral fellows.

Course Flyer

Course Schedule

Monday, May 13
    Female Reproductive Biology/Toxicology, Aileen Keating, Iowa State University

    Male Reproductive Biology/Toxicology, Justin Conley, US Environmental Protection Agency

    Embryology: From Fertilization to Neural Tube/Somite Formation, E. Sid Hunter III, US Environmental     Protection Agency

    Cellular and Molecular Analysis of Development, Joshua Robinson, University of California San Francisco

    Developmental Immunotoxicology, Jamie DeWitt, East Carolina University

    PK/ADME of Xenobiotics/Chemicals during Pregnancy/Lactation and in Fetus/Newborn, Hugh Barton,     Independent Consultant

Please join us for a reception following the class on Monday, May 13. This light-fare reception, which is included in the registration fee, allows for fellow course attendees, course organizers, and speakers to interact and network in a casual atmosphere. Hors d’oeuvres, plus drink tickets will be provided.

Tuesday, May 14
    Principles of Abnormal Development, Gerald Grunwald, Thomas Jefferson University

    Normal and Abnormal Development of the Musculoskeletal System and Limbs, John Rogers, US
    Environmental Protection Agency

    Normal and Abnormal Development of the Nervous System, Charles Vorhees, University of Cincinnati

    Normal and Abnormal Craniofacial Development, Robert Lipinski, University of Wisconsin

    Normal and Abnormal Development of the Respiratory and Digestive Systems, John DeSesso, Exponent

    Normal and Abnormal Development of the Cardiovascular System, John DeSesso, Exponent

    Normal and Abnormal Development of the Urogenital System, Michael Hsieh, George Washington University 

Wednesday, May 15
    Overview of Regulatory Reproductive and Developmental Toxicology, Alan Hoberman, Charles River

    Male/Female Fertility Testing, Donald Stump, Charles River

    Developmental Toxicity Testing, Christopher Bowman, Pfizer Inc.

    Pre- and Postnatal Development/Multigeneration Testing, Susan Makris, US Environmental Protection Agency

    Juvenile Animals Toxicity Testing, Susan Laffan, GlaxoSmithKline

    Data Interpretation, Alan Hoberman, Charles River

Thursday, May 16
    Risk Assessment for Pharmaceuticals, Tacey White, Aclairo Pharmaceutical Development Group, Inc.

    Risk Assessment for Agricultural and Industrial Chemicals, Anna Lowit, US Environmental Protection Agency

    Practicum: Case Studies
    Alan Hoberman, Charles River; Donald Stump, Charles River; John Rogers, US Environmental Protection Agency;     Christopher Bowman, Pfizer; and Susan Laffan, GlaxoSmithKline

    Practicum: Hands-On Exercise in Small Groups with Facilitators

    Practicum: Wrap-Up Discussion

Friday, May 17*
    Contemporary Reproductive and Developmental Toxicity Testing: New Approaches and     Methodologies, Aldert Piersma, Netherlands National Institute for Public Health and the Environment

    Future of Reproductive and Developmental Toxicity Testing: Computational and Organoids,
    Thomas Knudsen
, US Environmental Protection Agency

*Course ends at 12:00 Noon.

Daily continental breakfast, snack breaks, and lunch are provided as part of the registration. Detailed course handouts will be provided electronically. Participants must bring personal computer to view materials.

Times

Registration and Check-in: Monday, 7:30 AM–8:00 AM

Continental Breakfast: Monday, 7:30 AM–8:30 AM
                                       Tuesday, 7:30–8:00 AM
                                       Wednesday, 8:00 AM–8:30 AM
                                       Thursday, 7:30 AM–8:30 AM
                                       Friday, 8:00 AM–8:30 AM

Course: Monday, 8:30 AM–4:45 PM; Reception, 4:45 PM–6:30 PM
               Tuesday, 8:00 AM–5:30 PM
               Wednesday, 8:30 AM–4:30 PM
               Thursday, 8:00 AM–5:00 PM
               Friday, 8:30 AM–12:00 Noon

Course Organizers

Christopher Lau, PhD, US Environmental Protection Agency
Elaine Z. Francis, PhD, Sandcastle Toxicology Associates
Alan M. Hoberman, PhD, DABT, ATS, Charles River
John M. Rogers, PhD, US Environmental Protection Agency
Jordan BallanceACT staff liaison

Registration

Online Registration

Registration Form


Registration Fees:

  By March 10 March 11–May 10
ACT/Teratology Society Member $1,295 $1,395
ACT/Teratology Student and Postdoc Member $ 995 $1,095
Nonmember $1,595 $1,695
Government $1,295 $1,395
ACT/Teratology Society Member Group Rate**
(3 or more from same company)
$1,145 $1,245
Nonmember Group Rate**
(3 or more from same company)
$1,445 $1,545

**To take advantage of the group rate: Please send your completed registration forms to acthq@actox.org. You will not be able to select the group rate through the online registration.

Refund Policy:
$75 Processing Fee will be charged before 3/11/19; 50% refund if canceled before 4/8/19; After 4/8/19 no fees will be refunded.

Course Location

Gaithersburg Marriott Washingtonian Center
9751 Washingtonian Boulevard
Gaithersburg, MD 20878
Tel: 301.590.0044

Hotel

Gaithersburg Marriott Washingtonian Center
9751 Washingtonian Boulevard
Gaithersburg, MD 20878
Tel: 301.590.0044
Hotel Reservations: 800.228.9290

Housing Deadline:

Please refer to the ACT PRDT Room Block to make your housing reservation. The ACT PRDT meeting rate of $199 (plus tax) is offered over the dates of May 9–21, 2019, based on availability, and reservations must be made by April 15, 2019.

Requirements

A personal laptop to view course materials and your computer charger. We also suggest downloading all the course materials to your laptop, prior to arriving at the course. PRDT course materials will be provided approximately one week before the start of the course.


















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