American College of Toxicology


= Members Only

Educational Courses

Practical Reproductive and Developmental Toxicology

Hosted by the American College of Toxicology and Teratology Society, in collaboration with the Thomas Jefferson University College of Biomedical Sciences.

Course Description

This joint American College of Toxicology/Teratology Society course is designed to provide a basic understanding in reproductive and developmental biology and principles of various testing approaches for reproductive and developmental toxicology, with strong emphasis on the practical application of these principles and interpretation of nonclinical safety data as well as risk assessment. The intended audience for this course includes industrial and regulatory scientists, graduate students, and postdoctoral fellows.

Course Flyer

Course Schedule

Monday, May 8

Female Reproductive Biology/Toxicology, Aileen Keating, Iowa State University

Male Reproductive Biology/Toxicology, Justin M. Conley, US Environmental Protection Agency

Embryology: From Fertilization to Neural Tube/Somite Formation, E. Sid Hunter III, US Environmental Protection Agency

Cellular and Molecular Analysis of Development, Rocky S. Tuan, University of Pittsburgh

PK/ADME of Xenobiotics/Chemicals during Pregnancy/Lactation and in Fetus/Newborn, Hugh A. Barton, Pfizer Inc.

Please join us for a reception following the class on Monday, May 8. This light-fare reception, which is included in the registration fee, allows for fellow course attendees, course organizers, and speakers to interact and network in a casual atmosphere. Hors d’oeuvres, plus drink tickets will be provided.

Tuesday, May 9

Principles of Abnormal Development, Gerald B. Grunwald, Thomas Jefferson University

Normal and Abnormal Development of the Musculoskeletal System and Limbs, John M. Rogers,
US Environmental Protection Agency

Normal and Abnormal Development of the Nervous System, Charles V. Vorhees, University of Cincinnati

Normal and Abnormal Development of Head and Neck, Kathleen Sulik, University of North Carolina

Wednesday, May 10

Normal and Abnormal Development of the Respiratory and Digestive Systems, John M. DeSesso, Exponent

Normal and Abnormal Development of the Cardiovascular System, John M. DeSesso, Exponent

Normal and Abnormal Development of the Urogenital System, Michael Hsieh, George Washington University

Developmental Immunotoxicology, Michael Hsieh, George Washington University

Overview of Regulatory Reproductive Toxicology, Alan M. Hoberman, Charles River

Thursday, May 11

Male/Female Fertility Testing, Donald G. Stump, Charles River

Developmental Toxicity Testing, Christopher J. Bowman, Pfizer Inc.

Pre- and Postnatal Development/Multigeneration/Extended 1-Generation Testing, Susan L. Makris,
US Environmental Protection Agency

Data Interpretation, Alan M. Hoberman, Charles River

Future of Reproductive and Developmental Toxicity Testing, Thomas B. Knudsen, US Environmental Protection Agency

Friday, May 12*

Juvenile Animals Toxicity Testing, Susan B. Laffan, GlaxoSmithKline

Risk Assessment for Pharmaceuticals, Melissa S. Tassinari, Independent Consultant

Risk Assessment for Agricultural and Industrial Chemicals, Anna B. Lowit, US Environmental Protection Agency

*Course ends at 11:15 am.

Daily continental breakfast, snack breaks, and lunch are provided as part of the registration. Detailed course handouts will be provided electronically. Participants must bring personal computer to view materials.


Registration and Check-in: Monday, 7:30 AM–8:15 AM

Course: Monday, 8:15 AM–5:00 PM
               Tuesday, 8:15 AM–4:15 PM
               Wednesday, 8:15 AM–3:45 PM
               Thursday, 8:00 AM–4:15 PM
               Friday, 8:00 AM–11:15 AM

Course Organizers

Kok Wah Hew, PhD, DABT, ATS, Takeda Pharmaceuticals USA, Inc.
Elaine Z. Francis, PhD, Sandcastle Toxicology Associates
Alan M. Hoberman, PhD, DABT, ATS, Charles River
Christopher Lau, PhD, US Environmental Protection Agency


The 2017 course registration is now closed. For current course information visit the ACT course website.

Registration Fees:

  By March 10 March 10–May 4
ACT/Teratology Society Member $1,295 $1,395
ACT/Teratology Student and Postdoc Member $ 995 $1,095
Nonmember $1,595 $1,695
Government $1,295 $1,395
ACT/Teratology Society Member Group Rate
(3 or more from same company)
$1,145 $1,245
Nonmember Group Rate
(3 or more from same company)
$1,445 $1,545

Refund Policy:
$75 Processing Fee will be charged before 3/10/17; 50% refund if canceled before 4/7/17; After 4/8/17 no fees will be refunded.

Course Location

Thomas Jefferson University
Jefferson Alumni Hall
1020 Locust Street
Philadelphia, PA 19107


Holiday Inn Express Philadelphia Midtown—SOLD OUT
1305 Walnut Street
Philadelphia, PA 19107
Tel: 215.735.9300
Hotel Reservations: 888.752.5341

Housing Deadline:
Please refer to the ACT Group when booking. The ACT group block is sold out, but there are a limited number of rooms still available. Please contact the hotel directly or check their website for additional information on current available rates.

The Independent Hotel—SOLD OUT
1234 Locust Street
Philadelphia, PA 19107
Tel and Hotel Reservations: 215.772.1440

Housing Deadline: Please mention "the American College of Toxicology" when booking.

Holiday Inn Express Philadelphia Airport
101 Taylor Avenue
Essington, PA 19029
Tel and Hotel Reservations: 610.521.1200

Housing Deadline: Please refer to the American College of Toxicology when booking. The cut-off date to receive the group rate of $129 (plus tax) is April 1, 2017, but space is limited and the group rate is subject to availability.

Parking Information


A personal laptop to view course materials and your computer charger. We also suggest downloading all the course materials to your laptop, prior to arriving at the course. PRDT course materials will be provided approximately one week before the start of the course.

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