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Submission Guidelines

International Journal of Toxicology publishes timely, peer-reviewed papers on current topics important to toxicologists. Six bi-monthly issues cover a wide range of topics, including contemporary issues in toxicology, safety assessments, novel approaches to toxicological testing, mechanisms of toxicity, biomarkers, and risk assessment. The Journal also publishes invited reviews on contemporary topics, and features articles based on symposia. In addition, supplemental issues are routinely published on various special topics, including three supplements devoted to contributions from the Cosmetic Ingredient Review Expert Panel. The Journal does NOT publish the following: case reports, case studies, papers dealing with chemoprotection (i.e. the protective/therapeutic effect of agent X against the toxicity of chemical Y), papers showing results with poorly characterized natural products, or papers with an ecotoxicology focus.

Manuscripts should be submitted electronically to International Journal of Toxicology manuscript submission site. Authors will be asked to set up an online account in the SAGETRACK system, powered by ScholarOne. For questions regarding submission, contact Mary Beth Genter, Editor-in-Chief.

Style: International Journal of Toxicology follows the American Medical Association (AMA) format for text, citations, and references. Authors submitting manuscripts to International Journal of Toxicology should consult the 10th Edition of the AMA Manual of Style.

References must be numbered sequentially in the text, and listed in numerical order at the end of the text.

Typical entry for a journal article:

Brock WJ, Woolley AP, Sugimoto T. Certification in toxicology: an international perspective of risk:benefit. Int J Toxicol. 2009;28(3):147–50.

Typical entry for journal article with >six authors (list first three, then et al.):

Politano VT, Lewis EM, Hoberman AM, et al. Evaluation of the developmental toxicity of methyl dihydrojasmonate (MJD) in rats. Int J Toxicol. 2008;27(3):295–299.

Entry for book chapter:

Baker H, Genter MB. The olfactory system and nasal mucosa as portals of entry of viruses, drugs, and other exogenous agents into the brain. In: Doty RL, ed. Handbook of Olfaction and Gustation. 2nd ed. New York, NY: Marcel Dekker, Inc; 2003:549.

Submission: The following will be requested during online submission: (a) names, credentials, and complete contact information for the corresponding author; names, credentials, positions, and email addresses for all co-authors; (b) cover letter to the Editor stating explicitly that the manuscript is not under consideration by another journal; (c) abstract of 250 words or less; (d) key words; (e) abbreviations; and (f) one complete, double spaced Microsoft Word file of the article with the following components listed in order of appearance:

               Abstract
                  Main body of the article 
                       Introduction
                       Materials and Methods
                       Results
                       Discussion
                  Acknowledgements
                  Conflict(s) of interest
                  Figure legends
                  References
                  Tables

Figures will be uploaded separately and should meet the following criteria:
                  300 dpi or higher in resolution
                  .jpg or .tif files

Please keep in mind that manuscripts will not be reviewed until all necessary information has been submitted.

Conflict of Interest disclosure: Authors are required to disclose any possible conflicts of interest. Sufficient disclosure may include divulging affiliation as members of industrial or governmental organizations, academic support, non-profit consulting, advocacy, and all sources of financial and material support for studies and manuscripts submitted.

Guidelines for Ethical Publications: The American College of Toxicology Policy on the Use of Animals in Toxicology is published in Issue 1 each year, and copies may be requested from the Editor. Manuscripts submitted to International Journal of Toxicology should clearly state their compliance with the guidelines and principles listed therein.

Research involving human subjects: This work must be conducted with appropriate and competent oversight, such as provided by and Institutional Review Board (IRB), ethics committee (EC), or similar independent organization and must comply with the principles of the Declaration of Helsinki (World Medical Organization). The manuscript should state in the Methods section how participants were recruited and whether participants gave informed consent; the IRB or EC approval number must be included. In addition, information must be included in the manuscript that clearly states the number of human subjects recruited and describe the study procedures and data collection techniques. The Editor reserves the right to examine such documentation. No paper will be considered for review and publication without this information from the authors.

Guidelines for manuscripts describing natural products/natural products extracts: International Journal of Toxicology receives numerous submissions that focus on natural products or derivatives (most commonly extracts). In order to ensure the scientific reproducibility and quality of these submissions, the following parameters, at a minimum, must be addressed in the manuscript: (a) source and availability of material [including whether wild or cultivated]; (b) selection of material [in the case of plants, the plant selected for collection should be taxonomically the same as recommended by the national pharmacopeia or other related document]; (c) collection of the material; (d) processing and preparation of material; (e) storage conditions; (f) method(s) used to assure stability; (g) phytochemical analysis of the material, or other analytical evaluation that demonstrates the composition of the material. Excellent guidance on preparation and testing of natural products, their extracts, etc. has been detailed by the World Health Organization and the Foundation for Medical Research, India.

Where can authors post their manuscripts? Our publisher SAGE has recently adopted RoMEO Green compliant author archiving policy. The following applies under this new policy:

  • You retain copyright in your work.
  • You may do whatever you wish with the version of the article you submitted to the journal (version 1).
  • Once the article has been accepted for publication, you may post the accepted version (version 2) of the article on your own personal website, your department’s website or the repository of your institution without any restrictions.
  • You may not post the accepted version (version 2) of the article in any repository other than those listed above (i.e. you may not deposit in the repository of another institution or a subject repository) until 12 months after publication of the article in the journal.
  • You may use the published article (version 3) for your own teaching needs or to supply on an individual basis to research colleagues, provided that such supply is not for commercial purposes.
  • You may use the published article (version 3) in a book you write or edit any time after publication in the journal.
  • You may not post the published article (version 3) on a website or in a repository without permission from SAGE.
  • When posting or re-using the article please provide a link to the appropriate DOI for the published version of the article on SAGE Journals.

















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