International Journal of Toxicology


Volume 17, Supplement 2
June 1998


CONTENTS
Acknowledgements and Introductory Remarks by Co-Authors, W. T. Allaben and R. W. Hart
A mechanistic basis for the beneficial effects of caloric restriction on longevity and disease. Consequences for interpretation of rodent toxicity studies
J. E. A. Leakey, J. E. Seng, C. R. Baranas, V. M. Baker and R. W. Hart
Influence of Origin or Controlled Feeding on Longevity of Sprague-Dawley Rats
E. V. Knight, D. S. Barrett, C. M. Keenan, J. P. Kimball, B. H. Eitzen, S. Bryant, L. N. Smith, R. J. Szot and W. J. Powers
Body Weight and Disease in Chronic Tests
A. Turtorro, B. Hass, R. Hart and W. T. Allaben
The Effects of Diet and Overfeeding on Body Weight and Survival in the Rodent Bioassay: The Impact on Pharmaceutical Safety Assessment
K. P. Keenan
The National Toxicology Program Experience with Dietary Restriction: Does the Manner in which Reduced Body Weight is Achieved Affect Tumor Incidence?
J. K. Haseman



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